ParkinsonV1, Main, Exploration, bibRecord, 001802

Botulinum toxin B reduces sialorrhea in parkinsonism

Identifieur interne : 001802 ( Main/Exploration ); précédent : 001801; suivant : 001803

Botulinum toxin B reduces sialorrhea in parkinsonism

Auteurs : Brad A. Racette [États-Unis] ; Laura Good [États-Unis] ; Sandy Sagitto [États-Unis] ; Joel S. Perlmutter [États-Unis]

Source :

Movement Disorders [ 0885-3185 ] ; 2003-09.

RBID : ISTEX:5DDE62BE4CADD7BF7DB39AAD95B269F424A01FEF

English descriptors

KwdEn :
- botulinum toxin B, parkinsonism, sialorrhea.

Abstract

We report on our open‐label experience with botulinum toxin B for the treatment of severe sialorrhea associated with parkinsonism. Nine adult patients with parkinsonism and medically intractable sialorrhea were treated with botulinum toxin B (1,000 units into each parotid gland using superficial landmarks). After treatment, patients experienced a 61% mean subjective improvement and a 42% mean reduction of quantitative saliva production. There were no adverse effects seen in any subjects. Mean peak benefit from injections lasted 14 weeks. We conclude that denervation of salivary glands with botulinum toxin B produces excellent reduction of excessive salivation associated with parkinsonism. © 2003 Movement Disorder Society

Url:

https://api.istex.fr/document/5DDE62BE4CADD7BF7DB39AAD95B269F424A01FEF/fulltext/pdf

DOI: 10.1002/mds.10484

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="en">We report on our open‐label experience with botulinum toxin B for the treatment of severe sialorrhea associated with parkinsonism. Nine adult patients with parkinsonism and medically intractable sialorrhea were treated with botulinum toxin B (1,000 units into each parotid gland using superficial landmarks). After treatment, patients experienced a 61% mean subjective improvement and a 42% mean reduction of quantitative saliva production. There were no adverse effects seen in any subjects. Mean peak benefit from injections lasted 14 weeks. We conclude that denervation of salivary glands with botulinum toxin B produces excellent reduction of excessive salivation associated with parkinsonism. © 2003 Movement Disorder Society</div>
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Botulinum toxin B reduces sialorrhea in parkinsonism

Botulinum toxin B reduces sialorrhea in parkinsonism

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri